When running on natural gas, the fuel consumption of the 115 kW (156 hp) B 200 Natural Gas Drive stands at only 4.2 kg/100 km – corresponding to CO₂ emissions of 115 g per kilometre. The emission figures are thus about 16 percent lower than those of the petrol-driven B 200 BlueEFFICIENCY, which offers equivalent performance. The new model is classified as an efficiency class A vehicle and meets the EURO 6 emissions standard. But it is not only the environment that benefits - your wallet does too: If you convert the consumption of the B 200 Natural Gas Drive into the energy equivalent of petrol, the resulting  price per kilometre is about 50 percent lower than the fuel costs for covering the same distance in the petrol model.

Performance is on a similarly dynamic level: the B 200 Natural Gas Drive can reach speeds of up to 200 km/h, and accelerates from 0 to 100 km/h in 9.1 seconds (with 7G-DCT automatic transmission; with six-speed manual transmission the figure is 9.2 seconds). The B 200 Natural Gas Drive operates according to the monovalent+ principle. This means that its engine generally runs on gas. For emergencies, however, there is a small 12-litre petrol tank on board. In the event that the gas tank should ever run dry, the vehicle switches automatically, and imperceptibly, to petrol operation. As the driver is not able to select petrol mode himself/herself, the B 200 Natural Gas Drive is taxed more favourably as a natural gas vehicle. The range in natural gas mode is around 500 kilometres.

The trip computer menu in the instrument cluster has been extended in the case of the B 200 Natural Gas Drive: the respective operating mode is displayed. In addition, a fill level indicator and remaining range are included for petrol mode. In gas mode, the driver has access to all of the regular trip computer functions.

Vehicles fitted with natural gas drive are not only particularly environmentally friendly, they are also sustainable. This is because in addition to mineral natural gas, they can also be operated using biogas. Even synthetically produced gas can be used: this is produced using "excess" energy from solar power plants or wind farms, and in the future could help to resolve the storage problems encountered with alternative power generation. In this respect, taken overall, the B 200 Natural Gas Drive can be considered to be emission-free.